Ketamine use continues to present a growing challenge across services. One of the consistent issues raised by practitioners is that ketamine does not sit comfortably within existing substance misuse frameworks. Presentations often involve a mix of psychological drivers, complex patterns of use, and increasingly significant physical harm — particularly urological symptoms — that are not well captured by standard assessment tools. This creates a particular problem across differ

Positive psychological effects associated with taking small doses of psychedelic drugs are likely the result of users' expectations,...

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the...

The US Food and Drug Administration has just approved esketamine as an anti-depressant. Esketamine is the S-enantiomer of ketamine,...

A study led by Massachusetts General Hospital (MGH) investigators identifies two subanesthetic dosage levels of the anesthetic drug...

Perhaps one for the "I-am-really-not-sure-about-this-file" but a trial is going to examine whether high dose ketamine can help people in...