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Lean and Purple Drank: What Is It and How Common Is It in the UK?
Lean—also known as purple drank, dirty Sprite, sizzurp or simply syrup—is a drink usually associated with American hip-hop culture. Images of brightly coloured liquid in polystyrene cups have helped turn it into a recognisable cultural symbol, particularly on social media. Behind the branding, however, lean is essentially a form of opioid use. What is lean? The traditional American version is made by mixing cough syrup containing codeine and promethazine with a fizzy drink. S
Phil Harris
Aug 45 min read


Micro-Dosing: All in the Mind?
Positive psychological effects associated with taking small doses of psychedelic drugs are likely the result of users' expectations,...
Phil Harris
Mar 7, 20213 min read


ADHD & College Achievement
According to a 2017 UCLA study, students with ADHD make up about 6% of the college student population and represent the most common type...
Phil Harris
Feb 24, 20213 min read


Buvidal: A One Shot Opiate Replacement Therapy
Lockdown has had a big impact on everyone but especially those who are in receipt of opiate prescribing treatments. Daily administration...
Phil Harris
May 21, 20203 min read


Esketamine-The First Ketamine-Based Anti-Depressant Approved in US
The US Food and Drug Administration has just approved esketamine as an anti-depressant. Esketamine is the S-enantiomer of ketamine,...
Phil Harris
Mar 6, 20202 min read


AI: Predicts Responsiveness to Depression Treatment
Artificial intelligence may soon play a critical role in choosing which depression therapy is best for patients. A national trial...
Phil Harris
Feb 12, 20203 min read


Infection: What Role Does it Have in Schizophrenia?
My first day back at work in 2020 was with a fantastic team of mental health housing workers. We had an extensive debate on the role of...
Phil Harris
Jan 14, 20206 min read


Monthly Subutex Shots: Is It a Game Changer for Opiate Treatment?
Can a monthly injection of Subutex improve outcome rates for opiate users in treatment? Findings produces an interesting review of a...
Phil Harris
Apr 13, 20191 min read


New Approach to Over-Writing Trauma Memory
Traumatic experiences can become deeply entrenched in a person's memory. How can fears following a traumatic event be reduced in the long...
Phil Harris
Dec 13, 20183 min read


PTSD Eminently Treatable Research Shows
A multiyear clinical trial comparing medication and mental health counseling in the treatment of post-traumatic stress disorder shows...
Phil Harris
Oct 21, 20184 min read


Ketamine Demonstrates Effectiveness for Treatment Resistant Depression
A study led by Massachusetts General Hospital (MGH) investigators identifies two subanesthetic dosage levels of the anesthetic drug...
Phil Harris
Oct 15, 20183 min read


A Revolution in Diagnosis of Mental Illness?
In lectures and training in mental health I stress how current psychiatric diagnosis is really a short-hand for the presenting signs and...
Phil Harris
Oct 15, 20181 min read


Do Hallucinogens Hold Promise for Treating Mental Health Conditions?
Many people think of psychedelics as relics from the hippie generation or something taken by ravers and music festival-goers, but they...
Phil Harris
Aug 10, 20183 min read


Mental Health: Beyond Neurotranmission
Psychiatric medications have focused heavily on neurotransmitters as the basis of mental health disorders.Researchers at Columbia...
Phil Harris
Aug 9, 20182 min read


Spice Intoxication Reduced-By a Slimming Drug
The intoxicant effects of the synthetic cannabis Spice can be reduced. Early research from Queen Mary University of London has...
Phil Harris
Oct 9, 20171 min read


Placebo & Antidepressants
Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for depression and anxiety but their superiority over placebo has...
Phil Harris
Oct 9, 20172 min read


Schizophrenia: A Disease of the Immune System?
Recent developments in the area of immuno-psychiatry have begun to identify that prenatal viral infection may be responsible for the...
Phil Harris
Jun 7, 20171 min read
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